Development and Validation of Machine Learning Algorithms Based on Electrocardiograms for Cardiovascular Diagnoses at the Population Level

Development and Validation of Large-Scale Machine Learning Algorithms for Cardiovascular Diagnosis Based on Electrocardiograms Introduction Cardiovascular diseases (CV) have long been a major source of global disease burden. Early diagnosis and intervention are crucial for reducing complications, healthcare utilization, and associated costs. Tradit...

Prediction of tumor origin in cancers of unknown primary origin with cytology-based deep learning

Prediction of tumor origin in cancers of unknown primary origin with cytology-based deep learning

Background Introduction Cancer of Unknown Primary (CUP) is a type of malignant disease that is confirmed to be metastatic through histopathology but whose primary site cannot be identified using conventional baseline diagnostic methods. CUP presents significant diagnostic and therapeutic challenges in clinical practice and is believed to account fo...