TopoQA: A Topological Deep Learning-Based Approach for Protein Complex Structure Interface Quality Assessment

Academic Background The elucidation of protein complex 3D structures is a central topic in modern structural biology, molecular mechanism studies, drug design, and even artificial protein design. The function of a protein is often determined by its structure, and many biological processes involve complex interactions between proteins. Although trad...

Graph-Based Non-Sampling for Knowledge Graph Enhanced Recommendation

Graph-Based Non-Sampling for Knowledge Graph Enhanced Recommendation

Graph-Based Sampling-Free Knowledge Graph Enhanced Recommendation In recent years, knowledge graph (KG) enhanced recommendation systems, aiming to address cold start problems and the interpretability of recommendation systems, have garnered substantial research interest. Existing recommendation systems typically focus on implicit feedback such as p...