In Silico Modeling and Validation of the Effect of Calcium-Activated Potassium Current on Ventricular Repolarization in Failing Myocytes

Medicine, Basic Medical Sciences, Cardiovascular System, Life Sciences, Biochemistry, Bioengineering, Biophysics,
calcium-activated potassium channels   heart failure   ventricular repolarization   electrophysiological modeling   pharmacological modulation   arrhythmia   atrial fibrillation  

The Effect of Calcium-Activated Potassium Channels (SK Channels) on Repolarization in Failing Ventricular Myocytes—A Computational Modeling Study Research Background and Academic Significance Heart failure (HF) is a severe and prevalent cardiac disease, characterized by a comprehensive deterioration of the heart’s electrophysiological and contracti...