Multipotent Neural Stem Cells Originating from Neuroepithelium Exist Outside the Mouse Central Nervous System

Background Introduction For a long time, the scientific community has generally believed that mammalian neural stem cells (NSCs) exist only in the central nervous system (CNS), particularly in specific regions of the brain, such as the dentate gyrus of the hippocampus and the subventricular zone near the lateral ventricles. NSCs in these regions ca...

Disruption of G3BP1 Granules Promotes Mammalian CNS and PNS Axon Regeneration

Academic Background The regenerative capacity of the nervous system varies significantly between different regions. Axons in the peripheral nervous system (PNS) can regenerate spontaneously after injury, whereas axons in the central nervous system (CNS) lack this ability. This difference makes recovery after CNS injury extremely challenging, especi...