Academic Background In eukaryotic cells, the transport from the endoplasmic reticulum (ER) to the Golgi apparatus is a central process of the secretory system, responsible for the spatiotemporal sorting of proteins and lipids. However, the nature of the ER-Golgi intermediate compartment (ERGIC) and the molecular mechanisms mediating the transition ...

Targeting ERK1/2 and p38 MAPK Pathways Attenuates Golgin-97 Depletion-Induced Breast Cancer Progression Research Background Breast cancer is the most common type of cancer among women worldwide, with triple-negative breast cancer (TNBC) having a particularly high metastasis rate and poor prognosis. TNBC lacks expression of estrogen receptor, proges...