Assessing the Effects of Dasatinib on Mesenchymal Stem/Stromal Cells

Academic Background Mesenchymal Stem/Stromal Cells (MSCs) are a type of multipotent stem cells widely used in regenerative medicine and cell therapy. However, MSCs undergo progressive aging (senescence) during in vitro culture, leading to a decline in their proliferation and differentiation capabilities, which poses a significant obstacle to their ...

Role of Sirtuins in Obesity and Osteoporosis: Molecular Mechanisms and Therapeutic Targets

The Role of Sirtuins in Obesity and Osteoporosis and Their Therapeutic Potential Academic Background Obesity and osteoporosis (OP) are increasingly severe public health issues worldwide. Obesity is not only closely related to metabolic diseases such as cardiovascular diseases and diabetes but also has a complex association with the occurrence of os...