Background Introduction Ferroptosis is a form of cell death triggered by iron-dependent lipid peroxidation, which has recently been recognized as having significant potential in cancer therapy. Cancer cells evade ferroptosis through various molecular alterations and metabolic reprogramming mechanisms, with glutathione peroxidase 4 (GPX4) being a ke...

PRMT5-Regulated Splicing of DNA Repair Genes Drives Chemoresistance in Breast Cancer Stem Cells Academic Background Breast Cancer Stem Cells (BCSCs) are a rare subpopulation of cells within breast cancer that possess the ability to self-renew, initiate tumors, and metastasize. Despite their critical role in tumor initiation and progression, the mec...