Validation of a Prognostic Blood-Based Sphingolipid Panel for Men with Localized Prostate Cancer Followed on Active Surveillance

Study on a Prognostic Blood-Based Sphingolipid Panel for Men with Localized Prostate Cancer on Active Surveillance Academic Background Prostate cancer is one of the most common cancers among men globally, particularly for those with low- and intermediate-risk prostate cancer, where active surveillance (AS) has become the preferred management strate...

MRI-Directed Micro-US–Guided Transperineal Focal Laser Ablation for Localized Prostate Cancer: A 1-Year Follow-Up Study

MRI-Guided Micro-US Transperineal Focal Laser Ablation for Localized Prostate Cancer: A 1-Year Follow-Up Study Academic Background Prostate cancer (PCA) is one of the most common malignancies among men worldwide. With the widespread adoption of prostate-specific antigen (PSA) screening, the diagnosis of low-risk prostate cancer has significantly in...

Coagulation Factor X Promotes Resistance to Androgen-Deprivation Therapy in Prostate Cancer

Study on the Role of Coagulation Factor X in Anti-androgen Resistance in Prostate Cancer Research Background Prostate cancer (PCa) is the second most common cancer in men worldwide and is one of the leading causes of cancer-related deaths. The occurrence and progression of prostate cancer are highly dependent on the androgen receptor (AR) signaling...

Targeting HSP90AB1 and PARP1 to Enhance Anticancer Therapy in Prostate Cancer

Therapeutic Potential of Synergistic Targeted Inhibition of HSP90AB1 and PARP1 in Prostate Cancer Cells: A Review of Celastrol and Olaparib Combination Therapy Background Prostate Cancer (PCA) is one of the most common malignancies among men worldwide, with its incidence continually rising in recent years, making early screening and treatment cruci...

Prospective Study of Homologous Recombination Repair Gene Mutation Prevalence in Patients with Advanced Prostate Cancer from Latin America: Challenges and Future Approaches

Academic Report for the Paper Titled “Prospective Study of Homologous Recombination Repair Gene Mutation Prevalence in Patients with Advanced Prostate Cancer from Latin America: Challenges and Future Approaches” Background Prostate cancer is one of the most common cancers among men in Latin America and the Caribbean (LAC). According to the 2020 Glo...