Hypoxic Preconditioned ADSC Exosomes Enhance Vaginal Wound Healing via Accelerated Keratinocyte Proliferation and Migration through Akt/HIF-1α Axis Activation

Vaginal wound healing is a critical issue in gynecological surgery, especially following vaginal delivery or pelvic reconstructive surgery. Infection and poor healing of vaginal wounds can lead to severe complications such as chronic pain, infection, and dysfunction. Therefore, accelerating vaginal wound healing has been a focal point of clinical r...

Senescent Lung Fibroblasts in Idiopathic Pulmonary Fibrosis Facilitate Non-Small Cell Lung Cancer Progression by Secreting Exosomal MMP1

Academic Background and Problem Statement Idiopathic Pulmonary Fibrosis (IPF) is a progressive interstitial lung disease associated with aging and is an independent risk factor for lung cancer. Epidemiological studies indicate that 3%-22% of IPF patients develop lung cancer during follow-up, with the cumulative incidence increasing over time, makin...