IL-12 Drives the Differentiation of Human T Follicular Regulatory Cells

Review on the Study of IL-12 Promoting Human Follicular Regulatory T Cell Differentiation Research Background Follicular helper T cells (Tfh) play a crucial regulatory role in B cell responses to pathogens and vaccines. When not properly controlled, Tfh cells can lead to the production of antibodies against self-antigens or allergens. Follicular re...

Cytokines Drive the Formation of Memory-Like NK Cell Subsets via Epigenetic Rewiring and Transcriptional Regulation

Cytokines Drive the Formation of Memory-Like NK Cell Subsets via Epigenetic Rewiring and Transcriptional Regulation

In the context of today’s rapid advancement in science and technology, immunotherapy with natural killer (NK) cells has attracted widespread attention in the scientific community for their potential advantages in combating tumors and viral infections. Especially, the discovery of memory-like NK cells has brought new hope for NK cells as an anticanc...