Large-scale plasma proteomic profiling unveils diagnostic biomarkers and pathways for Alzheimer's disease

1. Research Background and Academic Significance Alzheimer’s Disease (AD) is the most common form of dementia worldwide, accounting for about 60–80% of all dementia cases. The primary affected population is individuals over 65 years old, with characteristic pathological features including the deposition of amyloid-β plaques, neurofibrillary tangles...

Multi-Template Meta-Information Regularized Network for Alzheimer’s Disease Diagnosis Using Structural MRI

Multi-Template Meta-Information Regularized Network for Alzheimer’s Disease Diagnosis Using Structural MRI

Multi-template Meta-information Regularized Network for Alzheimer’s Disease Diagnosis: A Study Based on Structural MRI Research Background Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder, and its diagnosis and early detection is a significant challenge in the medical field. Structural MRI (sMRI) is widely used in computer-aided...