NF-κB-Mediated Developmental Delay Extends Lifespan in Drosophila

Medicine, Rheumatology and Immunology, Endocrinology, Life Sciences, Cell Biology, Immunology, Genetics,
developmental delay   lifespan extension   NF-κB signaling   innate immunity   Drosophila  

1. Research Background Aging has long been viewed as a gradual decline in physiological function with age. However, mounting evidence indicates that developmental programs profoundly influence aging outcomes. For instance, developmental time (the time required for an organism to reach maturity) shows a significant positive correlation with adult li...

Intermittent clearance of p21-highly-expressing cells extends lifespan and confers sustained benefits to health and physical function

Medicine, Geriatrics, Cardiovascular System, Life Sciences, Cell Biology, Immunology,
p21-high cells   lifespan extension   health improvement   physical function   anti-aging   inflammation reduction  

Intermittent Clearance of High p21-Expressing Cells Extends Lifespan and Delivers Sustained Health Benefits Research Background With the significant extension of human lifespan, the global elderly population is rapidly increasing. Elderly individuals often face decreased functionality and various chronic diseases in their later years, such as cardi...