Alzheimer’s Disease and Age-Related Macular Degeneration: Shared and Distinct Immune Mechanisms

Academic Background Alzheimer’s disease (AD) and age-related macular degeneration (AMD) are the leading causes of cognitive impairment and vision loss in the elderly population worldwide. Although they affect different organs (the brain and the retina, respectively), recent studies have revealed shared pathological features, such as β-amyloid (Aβ) ...

Botulinum Neurotoxin Serotype A Inhibited Ocular Angiogenesis through Modulating Glial Activation via SOCS3

Academic Background Age-related macular degeneration (AMD) is a major cause of central vision loss among the elderly, particularly in its neovascular (NV) form, where choroidal neovascularization (CNV) leads to rapid and severe vision loss. Current AMD treatments primarily rely on intravitreal injections of anti-vascular endothelial growth factor (...