1. Academic Background—Innovative Diagnostic Tools Urgently Needed for Early Glaucoma Screening Glaucoma is one of the major diseases leading to irreversible blindness worldwide. According to studies such as [31], glaucoma is characterized by hidden early symptoms and irreversible visual impairment, making early detection and intervention crucial. ...

Academic Background Alzheimer’s disease (AD) and age-related macular degeneration (AMD) are the leading causes of cognitive impairment and vision loss in the elderly population worldwide. Although they affect different organs (the brain and the retina, respectively), recent studies have revealed shared pathological features, such as β-amyloid (Aβ) ...

Research Background In recent years, the incidence of myopia has risen dramatically worldwide, particularly in East Asia, where it has become a significant public health issue. Studies suggest that nearly 50% of the global population may suffer from myopia by 2050. Myopia not only causes blurred vision but is also closely associated with various bl...

High-precision Base Editing Technology in Primates and Human Retina Research Background Stargardt disease is a currently untreatable, inherited neurodegenerative disease that leads to macular degeneration and blindness due to loss-of-function mutations in the ABCA4 gene. The protein encoded by the ABCA4 gene is a membrane lipid flippase localized i...

Accelerating Multi-Electrode Array Simulation with Sparse and Low-Rank Matrix Techniques Academic Background Multi-electrode arrays (MEAs) play a crucial role in the field of neural stimulation, particularly in neural prosthetics such as retinal prostheses. These devices restore vision or treat neurodegenerative diseases by electrically stimulating...