Synthesis and Characterization of Pyrogallol Silver Nanoparticles and Pyrogallol Nanocomposites and Their Effects on Radiation-Induced Toxicity in HEK293 Cells

Chemistry, Nanoscience, Medicinal Chemistry, Medicine, Oncology, Life Sciences, Bioengineering,
nanoparticles   nanocomposites   radiation   cell protection   anti-inflammatory   apoptosis   biomedical applications  

Academic Background Cancer is a complex and highly prevalent disease worldwide, causing nearly 10 million deaths annually. Early diagnosis and effective treatment are crucial for improving patient survival rates. Current cancer treatment modalities include surgery, chemotherapy, radiotherapy, and immunotherapy. Among these, radiotherapy is a critic...

Hypoxia- and Postirradiation Reoxygenation-Induced HMHA1/ARHGAP45 Expression Contributes to Cancer Cell Invasion in a HIF-Dependent Manner

Medicine, Oncology, Life Sciences, Cell Biology, Biochemistry, Immunology,
hypoxia   radiation   reoxygenation   cancer cell invasion   HIF-dependent   HMHA1   ARHGAP45  

Contribution of HMHA1/ARHGAP45 Expression Induced by Hypoxia and Post-Radiation Reoxygenation to Cancer Cell Invasion: An HIF-Dependent Mechanism Background and Motivation Prior studies have extensively demonstrated that cancer cells in solid tumors acquire malignant characteristics such as invasiveness and treatment resistance under hypoxic condit...