Antigen Spatial-Matching Polyaptamer Nanostructure to Block Coronavirus Infection and Alleviate Inflammation

Academic Background In recent years, multiple outbreaks caused by coronaviruses have occurred globally, such as SARS (Severe Acute Respiratory Syndrome), MERS (Middle East Respiratory Syndrome), and COVID-19 (Novel Coronavirus Pneumonia). These pandemics have not only posed a serious threat to human health but also exposed the inadequacy of emergen...

Live Bacterial Chemistry in Biomedicine

Background Introduction The application of live bacteria in the biomedical field has garnered significant attention in recent years. Traditionally, bacteria were viewed as pathogens that needed to be eradicated. However, with the advancement of modern bacteriology, there has been a growing recognition of the complex symbiotic relationship between b...

Pseudomonas fluorescens–Based Biogenic Silver Nanoparticles: A Green Solution for Brown Leaf Spot Disease in Rice

Academic Background Rice (Oryza sativa L.) is a globally important food crop, providing a primary source of calories for approximately one-fifth of the world’s population. However, rice production faces various biotic and abiotic stresses, leading to reduced yields. Among these, rice brown leaf spot disease, caused by the fungal pathogen Cochliobol...

Development and Characterization of Baricitinib Nanoemulgel with Antiarthritic Effect in Rats

Academic Background Rheumatoid Arthritis (RA) is a chronic autoimmune disease that primarily affects the synovial membrane of joints, leading to inflammation and erosive lesions. Approximately 0.5% to 1% of the global population is affected by this disease, particularly among the elderly, who often experience dysphagia, which limits the compliance ...

Synthesis and Characterization of Pyrogallol Silver Nanoparticles and Pyrogallol Nanocomposites and Their Effects on Radiation-Induced Toxicity in HEK293 Cells

Academic Background Cancer is a complex and highly prevalent disease worldwide, causing nearly 10 million deaths annually. Early diagnosis and effective treatment are crucial for improving patient survival rates. Current cancer treatment modalities include surgery, chemotherapy, radiotherapy, and immunotherapy. Among these, radiotherapy is a critic...