Inflammatory Mechanisms in Traumatic Brain Injury and Post-Traumatic Epilepsy: A Study

Neuroinflammation and Epilepsy: The Role of Inflammasomes in Traumatic Brain Injury Background and Purpose Traumatic Brain Injury (TBI) refers to changes in brain function and pathology resulting from physical trauma to the head or neck. Apart from common behavioral and psychological disorders, post-traumatic epilepsy (PTE) is one of the most sever...

Early Depletion of Gut Microbiota Shapes Oligodendrocyte Response After Traumatic Brain Injury

Study on the Role of Gut Microbiota in White Matter Repair after Traumatic Brain Injury - Analysis of “Journal of Neuroinflammation” Introduction Every year, around 1.7 million people in the United States experience traumatic brain injury (TBI), with over 5 million facing disability issues related to TBI. These non-fatal TBIs are estimated to incur...

Systemic Administration of Soluble Glycoprotein 130 in Traumatic Brain Injury: Effects on Cognitive Performance and Chemokine Levels

Research Review: Treating Traumatic Brain Injury through Selective Inhibition of IL-6 Pathway Background Traumatic brain injury (TBI) is one of the leading causes of long-term neurological damage and death globally, with no effective disease-modifying treatments currently available. TBI patients often suffer from cognitive, behavioral, and sensory ...

Prevotella copri Transplantation Promotes Neurorehabilitation in a Mouse Model of Traumatic Brain Injury

Journal of Neuroinflammation Research Report: Neuroprotective Effects of Prevotella copri Transplantation in a Traumatic Brain Injury Mouse Model Background Traumatic brain injury (TBI) affects over 50 million people globally each year and is considered a significant public health challenge. Secondary injuries associated with TBI are largely relate...

Study on the Effects of Traumatic Brain Injury on Chronic Meningeal CLIP+ B Cells, Neuropathology, and Neurobehavioral Impairment in 5xFAD Mice

Research Report: Long-Term Effects of Class II Invariant Peptide (CLIP) Antagonism on CLIP+ B Cells in the Meninges, Neuropathology, and Neurobehavioral Deficits in 5xFAD Mice Research Background Traumatic brain injury (TBI) is a significant public health problem affecting millions of individuals worldwide each year. More importantly, TBI is a sign...