Psychedelic 5-HT2A Receptor Agonism Alters Neurovascular Coupling and Differentially Affects Neuronal and Hemodynamic Measures of Brain Function

Mechanisms of Psychedelics in Neurovascular Coupling: A Latest Research Interpretation 1. Academic Background and Research Motivation In the past decade, psychedelics such as psilocybin and lysergic acid diethylamide (LSD) have regained high attention in the scientific community due to their rapid and significant efficacy in clinical fields such as...

Functional Connectivity Analysis of Children with Autism Under Emotional Clips

Functional Connectivity Analysis of Children with Autism under Emotional Stimulation Background Introduction Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder, primarily characterized by deficits in social interaction and communication abilities, as well as repetitive behaviors and restricted interests. One of the core feature...

Amyloid-Associated Hyperconnectivity Drives Tau Spread Across Connected Brain Regions in Alzheimer’s Disease

Amyloid-Associated Hyperconnectivity Drives Tau Spread in Alzheimer’s Disease Academic Background Alzheimer’s Disease (AD) is a common neurodegenerative disorder characterized by the accumulation of amyloid-beta (Aβ) plaques and the abnormal aggregation and spread of tau protein in the brain. The traditional “amyloid cascade hypothesis” posits that...

Effects of Tactile Feedback in Post-Stroke Hand Rehabilitation on Functional Connectivity and Cortical Activation

Effects of Tactile Feedback in Post-Stroke Hand Rehabilitation on Functional Connectivity and Cortical Activation

A Neurofunctional Study of Tactile Feedback in Stroke Rehabilitation Based on fNIRS Academic Background Stroke is a common neurological condition that profoundly affects patients’ daily lives and quality of life. Among the various functional impairments caused by stroke, hand dysfunction is particularly notable, manifesting in decreased muscle stre...

Relationship Between Structural and Functional Network Connectivity Changes for Patients with Traumatic Brain Injury and Chronic Health Symptoms

Study on Structural and Functional Network Connectivity Changes in Patients with Traumatic Brain Injury Background Introduction Traumatic Brain Injury (TBI) is a common neurological disorder that can lead to long-term cognitive, emotional, and physical symptoms. Although many patients experience symptom relief within months after the injury, a sign...

Topological Features of Brain Functional Networks Are Reorganized During Chronic Tinnitus: A Graph-Theoretical Study

Reorganization of Topological Features in Brain Functional Networks in Patients with Chronic Tinnitus Academic Background Tinnitus is the perception of sound in the absence of any external acoustic stimuli or internal sources of auditory perception, with a global prevalence ranging from 11.9% to 30.3%. Patients with tinnitus experience not only aud...