Academic Background One of the defining features of the adaptive immune system is its ability to generate highly diverse antigen receptors through V(D)J recombination, enabling recognition of a broad range of pathogenic threats. The traditional view holds that somatic hypermutation (SHM) in germinal centers (GCs) can only optimize pre-existing anti...

Developing a Novel Erythrocyte-MHC-I Conjugate for Cancer Treatment: A Revolutionary Immunotherapy Research Background: Traditional Roles and Newly Discovered Potential Erythrocytes, or red blood cells, are the most abundant cells in the human body, comprising approximately 70% of total cell count in adults. Traditionally recognized for their role ...

Research Background Multiple Sclerosis (MS) is a common disease involving lesions in the central nervous system, characterized mainly by demyelination of neuronal axons and neuronal damage. The heterogeneity of the disease is extremely high, meaning that different patients exhibit varying symptoms and pathological mechanisms, which greatly complica...