Integration and Competition Between Space and Time in the Hippocampus

A Review on the Mechanisms of Spatial and Temporal Integration and Competition in the Hippocampus Research Background and Significance In the human and animal brain, space and time comprise the primary dimensions of episodic memory, playing a crucial role in encoding information such as event sequences, locations, and durations. It has long been fo...

Mechanism of Myosin Va-Dependent Transport of NMDA Receptors in Hippocampal Neurons

Study on Myosin Va-dependent NMDA Receptor Transport Mechanism in Hippocampal Neurons In hippocampal neurons, NMDA receptors (N-Methyl-D-Aspartate Receptor, abbreviated as NMDAR) are a subtype of glutamate receptors, crucial for regulating postsynaptic responses and various brain functions. The number of NMDARs in the postsynaptic region can change...

Associations of Epigenetic Age Estimators with Cognitive Function Trajectories in the Women's Health Initiative Memory Study

Association Between Epigenetic Age Acceleration Estimates and Cognitive Trajectories in the Women’s Health Initiative Memory Study Background Maintaining cognitive function is crucial for independent living among older adults. With the growth of the aging population, cognitive decline has become a significant public health challenge. Many studies h...

Atypical Connectome Topography and Signal Flow in Temporal Lobe Epilepsy

Atypical Connectome Topography and Signal Flow in Temporal Lobe Epilepsy

Epilepsy is one of the most common neurological disorders, with temporal lobe epilepsy (TLE) being the most prevalent form of drug-resistant epilepsy in adults. Numerous studies have indicated that TLE involves not only pathological changes in the medial temporal lobe but also affects widespread brain structures and functions. In this scientific re...

Using Deep Neural Networks to Disentangle Visual and Semantic Information in Human Perception and Memory

Differentiating Visual and Semantic Information in Human Perception and Memory Using Deep Neural Networks Introduction In cognitive science, the study of how humans recognize individuals and objects during perception and memory processes has long been of interest. Successful recognition of people and objects relies on matching representations gener...