New Advances in Hippocampal Spatiotemporal Coding—Multiplexed Theta Phase Coding and the Regulation by External vs. Self-Motion Cues —Review of the latest Nature Neuroscience paper: “allothetic and idiothetic spatial cues control the multiplexed theta phase coding of place cells” 1. Academic Background & Motivations Spatial navigation and memory ha...
Chronic Toxoplasma Infection and Elevated IL-1 Lead to Hippocampal Dysfunction via DNA Double-Strand Break Signaling: A Review of the Latest Nature Neuroscience 2025 Study Academic Background and Research Rationale In recent years, neuroinflammation has garnered increasing attention in the academic community due to its role in various brain disease...
Cutting Baseline Research Report in Nature Neuroscience: Pancreas–Hippocampus Feedback Mechanism Regulates Circadian Rhythm and Depression-Related Behaviors 1. Introduction and Academic Background In recent decades, the comorbidity of neuropsychiatric disorders and metabolic dysregulation has become a research hotspot in neuroscience and psychiatri...
Academic Background Sleep plays a crucial role in memory formation, particularly non-rapid eye movement (NREM) sleep, which is considered a critical stage for memory consolidation. However, the specific mechanisms underlying memory consolidation, especially how intracellular signaling molecules coordinate with neural activity, remain a mystery. Cyc...
Alzheimer’s Disease (AD) is the most common form of dementia, characterized by the accumulation of amyloid-beta (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain, leading to the progressive deterioration of brain function. Although Aβ plaques and NFTs have long been considered hallmarks of AD pathology, therapeutic strategies targeting t...
Study on the Neuroregulatory Effects of Meditation: A Case Study of Loving-Kindness Meditation Academic Background Meditation, as a mental training technique, has long been believed to regulate emotions and enhance mental health. Specifically, Loving-Kindness Meditation (LKM), which focuses on cultivating positive emotions towards oneself and other...
The Impact of the Maternal X Chromosome on Cognition and Brain Aging in Female Mice Background Introduction In mammals, female cells possess two X chromosomes, one from the mother (maternal X chromosome, Xm) and one from the father (paternal X chromosome, Xp). During embryonic development, one of the X chromosomes is randomly inactivated, a process...