Research Background and Academic Significance Olfaction is one of the most important ways for humans to sense the external environment, fundamentally relying on olfactory sensory neurons (OSNs) in the olfactory epithelium (OE). These neurons possess the ability to regenerate throughout life, primarily due to the presence of local basal stem cell po...

1. Academic Background and Research Significance Human bone tissue possesses a certain degree of self-healing capability. However, after suffering from severe trauma, tumor resection, infection, or congenital deformity, leading to large-volume bone defects, this regenerative ability becomes limited. The so-called “critical size bone defect” refers ...

Establishment of a Personalized Antisense Oligonucleotide (ASO) Screening Platform Based on Patient-Derived Organoids Academic Background In recent years, with the rapid development of genome sequencing technologies, an increasing number of rare genetic diseases have been found to be associated with specific gene mutations. Antisense oligonucleotid...

3D Bioprinted Cellulose/Collagen-Based Drug-Eluting Fillers for the Treatment of Deep Tunneling Wounds Academic Background Deep tunneling wounds are complex injuries that form beneath the skin surface, varying in shape and size, and may have twists and turns, making treatment extremely challenging. Current wound care solutions primarily target supe...

In Vitro Model of Vertebrate Trunk Development Academic Background The development of the vertebrate trunk is a highly coordinated process involving the generation and organization of multiple cell types. At the core of this process are progenitor cells located in the posterior of the embryo, which differentiate into tissues such as the neural tube...