Isolation and Identification of Three New Isomer Impurities in Milbemycin Oxime Drug Substance

Isolation and Identification of Three New Isomer Impurities in Milbemycin Oxime Drug Substance Academic Background Milbemycins are a class of 16-membered macrolides produced by Streptomyces, exhibiting potent anthelmintic and insecticidal activities with low mammalian toxicity. Milbemycins and their derivatives are widely used in agriculture and ve...

Nonemissive Iridium(III) Solvent Complex as a Self-Reporting Photosensitizer for Monitoring Phototherapeutic Efficacy in a 'Signal On' Mode

Iridium(III) Solvent Complex as a Self-Reporting Photosensitizer for Monitoring Phototherapeutic Efficacy Academic Background Cancer is one of the leading causes of global mortality, significantly impacting patients’ quality of life. In recent years, photodynamic therapy (PDT) has garnered considerable attention as a promising technology for cancer...

Rapid and Large-Scale Synthesis of Chiral and Fluorescent Sulfur Quantum Dots for Intracellular Temperature Monitoring

Rapid and Large-Scale Synthesis of Chiral Fluorescent Sulfur Quantum Dots for Intracellular Temperature Monitoring Academic Background Fluorescent nanomaterials have broad application potential in fields such as energy harvesting, lighting displays, communication and information technology, biology, and medicine. Among them, sulfur quantum dots (SQ...

Laser-Treated Screen-Printed Carbon Electrodes for Electrochemiluminescence Imaging

Laser-Treated Screen-Printed Carbon Electrodes for Electrochemiluminescence Imaging Research Academic Background Electrochemiluminescence (ECL) is an analytical method that combines electrochemical and luminescent techniques, offering advantages such as high sensitivity, high selectivity, and low background noise. It is widely used in biosensing an...

Synthesis of Palladium Nanoparticles by Electrode-Respiring Geobacter sulfurreducens Biofilms

Synthesis of Palladium Nanoparticles by Electrode-Respiring Geobacter sulfurreducens Biofilms Research Background In modern industry and environmental science, palladium (Pd) serves as a crucial catalyst widely used in pharmaceuticals, agriculture, and chemical industries. However, traditional methods for synthesizing palladium nanoparticles (Pd NP...