Global Surveillance of Circulating MicroRNA for Diagnostic and Prognostic Assessment of Acute Myocardial Infarction Based on Plasma Small RNA Sequencing Academic Background Acute Myocardial Infarction (AMI) is one of the most severe cardiovascular diseases leading to human mortality and morbidity worldwide. The pathological mechanism of AMI primari...

Comprehensive Clinical and Preclinical Studies Reveal the Therapeutic Potential of Ferroterminator1 (FOT1) for Metabolic-Associated Fatty Liver Disease (MAFLD) Background: Research Needs on MAFLD and Iron Overload Issues Metabolic-associated fatty liver disease (MAFLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a common chroni...

Alzheimer’s Disease (AD) and Microbleeds in Down Syndrome (DS) Populations: Their Localization and Association with Imaging and Cerebrospinal Fluid (CSF) Biomarkers This study was conducted by a team led by Sara E. Zsadanyi and Alejandra O. Morcillo-Nieto, with contributors including Mateus R. Aranha, José E. Arriola-Infante, Lídia Vaqué-Alcázar,...

Differential Regulation of miR206 and miR423-3p in Rapidly and Slowly Progressing Amyotrophic Lateral Sclerosis Patients This article was published in the 2024 issue of “Neuromolecular Medicine,” titled “Differential Regulation of miR206 and 423-3p in Rapidly and Slowly Progressing Amyotrophic Lateral Sclerosis (ALS) Patients.” The authors include ...

Ovarian cancer is one of the most common and deadly tumor types in women. In recent years, Poly (ADP-ribose) polymerase inhibitors (PARPi) have shown encouraging clinical results in the treatment of ovarian cancer. Numerous studies have found that patients with homologous recombination deficiency (HRD) benefit more from PARPi treatment. Therefore, ...