I. Research Background and Scientific Question Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide, with pathological features mainly including neuronal loss, neurofibrillary tangles, and senile plaques (mainly formed by amyloid-β [Aβ] deposition). According to statistics, the number of AD patients continues to rise each...

Academic Background Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is a common cardiovascular disease, particularly among diabetic patients, whose incidence and mortality rates are significantly higher than those of non-diabetic patients. Although current clinical guidelines recommend early (within 24 hours) coronary revascularization ...

Academic Background Diabetes is a global health issue affecting over 500 million people. Both type 1 diabetes (T1D) and type 2 diabetes (T2D) share the common feature of a significant reduction in the number of functional insulin-secreting beta cells. Therefore, restoring or increasing beta cell mass is considered a key strategy in diabetes treatme...

Research Review on Aging-Exacerbated Metabolic Dysfunction-Related Lipid Liver Diseases Academic Background As the aging population increases, metabolic diseases induced by aging are becoming a severe public health challenge. The liver, being the primary metabolic organ, requires special attention to its functional disorders during aging. Studies h...