CHD2 Regulates Neuron-Glioma Interactions in Pediatric Glioma

Research Report on the Regulation of Neuron-Glioma Interactions by CHD2 in Pediatric Gliomas Background High-grade gliomas (HGG) are fatal diseases in both adult and pediatric patients. Recent studies have shown that neuronal activity can promote the progression of various high-grade glioma subgroups. However, the epigenetic mechanisms regulating t...

A prognostic neural epigenetic signature in high-grade glioma

Study of Neuroepithelial Genetic Markers and Prognosis in High-Grade Gliomas Background and Research Motivation High-grade gliomas are highly malignant brain tumors with generally poor patient prognosis. Previous preclinical model studies have suggested that interactions between neural and tumor cells drive tumor growth, but clinical validation of ...

An Explicit Estimated Baseline Model for Robust Estimation of Fluorophores Using Multiple-Wavelength Excitation Fluorescence Spectroscopy

Research Background Fluorescence spectroscopy is a widely used method for identifying and quantifying fluorescent substances (fluorophores). However, quantifying the fluorophores of interest becomes challenging when the material contains other fluorophores (baseline fluorophores), especially when the emission spectrum of the baseline is not well-de...

Evaluating the Predictive Value of Glioma Growth Models for Low-Grade Glioma after Tumor Resection

Research Review on the Predictive Value of Low-Grade Glioma Postoperative Growth Models Introduction Glioma is an aggressive brain tumor whose cells rapidly diffuse within the brain. Understanding and predicting the pattern and speed of this diffusion can help optimize treatment plans. Glioma growth models based on diffusion-proliferation have show...

Laser Interstitial Thermal Therapy in Neurosurgery: A Single-Surgeon Experience of 313 Patients

Laser Interstitial Thermal Therapy in Neurosurgery: A Single-Surgeon Experience of 313 Patients

Clinical Study Report on Laser Interstitial Thermal Therapy (LITT) in Neurosurgery Background Introduction With the continuous progress of modern medical technology, Laser Interstitial Thermal Therapy (LITT) has gradually gained a foothold in the field of neurosurgical tumor treatment, especially in treating intracranial lesions that are difficult ...