Seeding and Feeding Milestones: The Role of Human Milk Microbes and Oligosaccharides in the Temporal Development of Infant Gut Microbiota

The Key Role of Human Milk Microbes and Oligosaccharides in Infant Gut Microbiota Development Academic Background The development of infant gut microbiota is crucial in early life, and breastfeeding is one of the key drivers of this process. Human milk not only provides essential nutrients for infants but also contains a rich array of microbes and ...

Translocating Gut Pathobiont Enterococcus Gallinarum Induces Th17 and IgG3 Anti-RNA Directed Autoimmunity in Mouse and Human

Academic Background Chronic autoimmune diseases are typically triggered by a combination of genetic predisposition and environmental factors, with complex and incompletely understood mechanisms. In many cases, these diseases require lifelong immunosuppressive treatments, imposing a heavy burden on patients. Recent research has found that gut microb...

Achieving Healthy Aging Through Gut Microbiota-Directed Dietary Intervention: Focusing on Microbial Biomarkers and Host Mechanisms

Achieving Healthy Aging through Gut Microbiota-Directed Dietary Intervention: Focusing on Microbial Biomarkers and Host Mechanisms Academic Background With the intensification of global population aging, preventing age-related diseases and extending healthy life expectancy have become critical issues in global public health. Gut microbiota has been...

The Neonatal Gut Microbiota: A Role in the Encephalopathy of Prematurity

The Neonatal Gut Microbiota: A Role in the Encephalopathy of Prematurity

The Role of the Neonatal Gut Microbiota in the Encephalopathy of Prematurity: A Comprehensive Study Academic Background Premature birth (defined as birth before 37 weeks of gestation) is a common issue globally, affecting approximately 10% of pregnancies. Preterm infants are at risk of abnormal brain development, known as Encephalopathy of Prematur...

Gut Microbiota-Derived Indole-3-Acetic Acid Suppresses High Myopia Progression by Promoting Type I Collagen Synthesis

Gut Microbiota-Derived Indole-3-Acetic Acid (3-IAA) Suppresses High Myopia Progression by Promoting Type I Collagen Synthesis Background High myopia (HM) is a serious vision-threatening ocular condition associated with complications such as glaucoma, cataracts, and macular degeneration. Currently, effective interventions for high myopia are lacking...