Novel Heart Valve Leaflet Designs with Stiff Polymeric Materials and Biomimetic Kinematics

Novel Heart Valve Leaflet Design: Research Based on High-Stiffness Polymeric Materials and Biomimetic Kinematics Academic Background Heart valve disease is a significant global health issue, with over 850,000 patients requiring heart valve replacement surgery annually. Currently, the heart valves used in clinical practice are mainly divided into tw...

Electrospun Polyvinyl Alcohol Fibres Incorporating an Antimicrobial Gel for Enzymatically Controlled Reactive Oxygen Species Release

Study on Antimicrobial Gel Combined with Electrospun Polyvinyl Alcohol Fibers for Enzymatically Controlled Reactive Oxygen Species Release Academic Background The skin is the body’s first line of defense against infections, and the presence of wounds can compromise this barrier, increasing the risk of infection. With the rise of antibiotic resistan...

3D-Bioprinted Tri-Layered Cellulose/Collagen-Based Drug-Eluting Fillers for the Treatment of Deep Tunneling Wounds

3D Bioprinted Cellulose/Collagen-Based Drug-Eluting Fillers for the Treatment of Deep Tunneling Wounds Academic Background Deep tunneling wounds are complex injuries that form beneath the skin surface, varying in shape and size, and may have twists and turns, making treatment extremely challenging. Current wound care solutions primarily target supe...

Multimodal Imaging Unveils the Impact of Nanotopography on Cellular Metabolic Activities

The Impact of Nanotopography on Cellular Metabolic Activities: Multimodal Imaging Reveals New Insights Academic Background In the field of biomedicine, the interaction between cells and material surfaces is crucial for studying cell behavior, tissue engineering, and regenerative medicine. Nanoscale surface topography (nanotopography) has been shown...

Unraveling the Applicability of LBL Coatings for Drug Delivery in Dental Implant-Related Infection Treatment

Application of LBL Coatings in the Treatment of Dental Implant-Related Infections Background Dental implant-related infections, particularly peri-implantitis, are inflammatory diseases caused by bacterial biofilms, leading to progressive destruction of surrounding tissues. Peri-implantitis not only may result in implant loss but also can trigger mo...