Proteomic Subtyping of Small Cell Lung Cancer: Analysis of Prognosis and Treatment Strategies Research Background Small Cell Lung Cancer (SCLC) is a highly malignant and heterogeneous cancer characterized by rapid growth, early metastasis, and drug resistance, which limits treatment options and challenges prognostic prediction models. Current genom...

The Key Role of Retina Microglia in Pathological Angiogenesis and the Immunotherapeutic Potential of the cGAS-STING Pathway Background Pathological angiogenesis is common in various neovascular ophthalmic diseases, such as Diabetic Retinopathy (DR) and Age-related Macular Degeneration (AMD) [1]. During these diseases, bone marrow cells, including r...

Immunotherapy Checkpoint Inhibitors (ICIs, also known as immune checkpoint blockers) are a class of drugs that have achieved significant breakthroughs in cancer immunotherapy in recent years. These drugs mainly work by blocking Programmed Death Protein 1 (PD-1) and Cytotoxic T-lymphocyte-associated Protein 4 (CTLA-4), thereby activating anti-tumor ...

In the context of today’s rapid advancement in science and technology, immunotherapy with natural killer (NK) cells has attracted widespread attention in the scientific community for their potential advantages in combating tumors and viral infections. Especially, the discovery of memory-like NK cells has brought new hope for NK cells as an anticanc...

Research Report on Immunotherapy Efficacy Prediction for Non-Small Cell Lung Cancer: A Study of Multi-View Adaptive Weighted Graph Convolutional Networks Background Introduction Lung cancer is a highly prevalent and poorly prognostic malignant tumor with a persistently high mortality rate. Among all lung cancer patients, Non-Small Cell Lung Cancer ...