Protective Effect of Doxycycline-Loaded Calcium Phosphate Nanoparticles on LPS-Induced Neuroinflammation in Mice In the field of neuroscience research, neuroinflammation is an important pathological feature of many neurological diseases. Neuroinflammation is a complex response of the central nervous system (CNS) to various damaging triggers (such a...

Background Introduction Sterile neuroinflammation is an important factor driving various neurological diseases. Myelin debris, released during the demyelination process in various neurological diseases (such as stroke, spinal cord injury (SCI), multiple sclerosis (MS), traumatic brain injury (TBI), and neurodegenerative diseases), can act as an inf...

Research on Saturated Fatty Acids and Brain Function Background Introduction Obesity and metabolic syndrome are major global health challenges today. Numerous studies have shown that excessive consumption of diets rich in saturated fats leads to obesity, accompanied by a series of metabolic complications such as insulin resistance and diabetes. How...

Important Research Interpretation from “Journal of Neuroinflammation” 2024: The Impact of Park7/DJ-1 Deficiency on Microglial Activation Academic Background Parkinson’s Disease (PD) is the second most common neurodegenerative disease, characterized by the accumulation of α-synuclein and progressive loss of dopaminergic neurons. Aging is the primary...

Research Background Glaucoma is a major cause of blindness, characterized by complex neurodegenerative conditions that include extensive inflammatory responses in glial cells, accompanied by the progressive loss of Retinal Ganglion Cells (RGCs), optic nerve axons, and synaptic connections. Although there are variations in subtypes, topologies, and ...