Aging Promotes Reactivation of the Barr Body at Distal Chromosome Regions

1. Academic Background: The Mysterious Link between X Chromosome Inactivation and Aging In mammals, females possess two X chromosomes while males have only one. To maintain gene dosage balance between the sexes, females undergo a process called X chromosome inactivation (XCI) early in development, in which one of the two X chromosomes is randomly s...

Hemispheric Asymmetry of Intracortical Myelin Orientation in the Mouse Auditory Cortex

Hemispheric Asymmetry of Myelin Orientation in the Mouse Auditory Cortex Academic Background The mammalian brain exhibits inherent asymmetry, which is particularly evident in the motor system and acoustic communication. For example, both mice and humans show hemispheric differences in auditory processing. This asymmetric organization allows the bra...

Sex Differences in Olfactory Behavior and Neurophysiology in Long Evans Rats

Sex Differences in Olfactory Behavior and Neurophysiology in Long Evans Rats Academic Background Olfaction plays a crucial role in the survival and reproduction of many species. Studies have shown that females exhibit greater sensitivity in certain olfactory behaviors compared to males. For example, human females outperform males in olfactory thres...

Obesity Intensifies Sex-specific Interferon Signaling to Selectively Worsen Central Nervous System Autoimmunity in Females

Obesity Intensifies Sex-specific Interferon Signaling to Selectively Worsen Central Nervous System Autoimmunity in Females

Obesity Aggravates Female Central Nervous System Autoimmune Diseases Through Sex-Specific Interferon Signaling In recent years, the rising incidence of central nervous system (CNS) autoimmune diseases in females has garnered widespread attention. Obesity, as a potential environmental risk factor, has gradually become a research hotspot. The latest ...

Sex Differences in the Risk of Stroke Associated with Traditional and Non-Traditional Factors in a US Cohort of People with HIV Infection

Study on Gender Differences and Stroke Risk Among HIV-Infected Individuals Background Individuals with HIV infection may face a higher risk of stroke, particularly women. However, understanding of whether the influence of various factors on cerebrovascular risk in this population differs by gender and whether these differences contribute to variati...