Exosomes Derived from Exercise-Trained Mice Bone Marrow Mesenchymal Stem Cells Improve Wound Healing by Inhibiting Macrophage M1 Polarization

Medicine, Rheumatology and Immunology, Oral Sciences, Sports Medicine, Life Sciences, Cell Biology, Biochemistry, Bioengineering, Immunology,
bone marrow mesenchymal stem cells   exosome   treadmill exercise   macrophage polarization   M1   wound healing   inflammation  

I. Academic Background and Research Significance Wound healing is a highly complex physiological process that plays a crucial role in tissue regeneration, repair, and immune regulation. However, poor healing of chronic wounds is clinically widespread, severely impacting patients’ quality of life and increasing medical and socioeconomic burdens. The...

Treadmill Exercise Reshapes Cortical Astrocytic and Neuronal Activity to Improve Motor Learning Deficits Under Chronic Alcohol Exposure

Medicine, Psychiatry, Neurology, Life Sciences, Cell Biology,
alcohol abuse   motor learning   dendritic spine   reactive astrocyte   cortical neurons   treadmill exercise  

Background and Research Motivation Alcohol abuse is a global health issue, affecting over 8% of the male population. Prolonged alcohol exposure can alter the homeostasis of neurons and synapses in the brain, leading to various mental disorders and cognitive deficits, especially in motor learning. Previous studies have shown that alcohol abuse cause...