Preference Prediction-Based Evolutionary Multiobjective Optimization for Gasoline Blending Scheduling

Preference Prediction-Based Evolutionary Multiobjective Optimization for Gasoline Blending Scheduling Background Introduction With the continuous evolution of the global energy market, gasoline production and blending processes face increasing challenges. As a key product of the oil industry, gasoline’s blending and scheduling processes directly af...

Dual Ferroptosis Induction in N2-TANs and TNBC Cells via FTH1 Targeting: A Therapeutic Strategy for Triple-Negative Breast Cancer

Dual Ferroptosis Induction via FTH1 Targeting: A New Therapeutic Strategy for Triple-Negative Breast Cancer (TNBC) Background: Why Conduct This Study? Breast cancer is one of the most common cancer types worldwide, accounting for 11.7% of all new cancer cases globally. Among its several subtypes, triple-negative breast cancer (TNBC) stands out for ...

Enabling tumor-specific drug delivery by targeting the Warburg effect of cancer

Research on a New Platform for Tumor-Specific Drug Delivery Targeting the Warburg Effect Cancer remains a global health challenge. Traditional cancer treatments, such as chemotherapy and radiotherapy, often come with significant side effects due to their inability to distinguish between tumor tissues and healthy tissues, leading to damage in the la...

Mitochondrial Uncouplers Inhibit Oncogenic E2F1 Activity and Prostate Cancer Growth

Mitochondrial Uncouplers Inhibit Oncogenic E2F1 Activity and Prostate Cancer Growth

Research Report: Mitochondrial Uncouplers Inhibit E2F1 Activity and Prostate Cancer Growth Background Prostate cancer (PC) is the most common cancer and the second leading cause of cancer-related deaths among men in the United States. In 2024, an estimated 299,010 American men will be diagnosed with prostate cancer, and 35,250 will die from the dis...

Protein-functionalized and intrinsically radiolabeled 188Re oxide nanoparticles: advancing cancer therapy through concurrent radio-photothermal effects

Protein-Functionalized and Intrinsically Radiolabeled [188Re]ReOx Nanoparticles: Breakthrough Application in Multimodal Synergistic Cancer Therapy Cancer remains one of the leading causes of death globally, despite significant progress in medical science over the past few decades. However, early detection and treatment methods still face significan...