Nonlinear Coupling of Closely Spaced Modes in Atomically Thin MoS2 Nanoelectromechanical Resonators

Study of Nonlinear Coupling in Atomically Thin MoS₂ Nanoelectromechanical Resonators Academic Background With the rapid development of nanotechnology, Nanoelectromechanical Systems (NEMS) have shown great potential in fields such as sensors, signal processing, and quantum computing. Particularly, two-dimensional (2D) materials like molybdenum disul...

Advancement in Piezoelectric Nanogenerators for Acoustic Energy Harvesting

Advancement in Piezoelectric Nanogenerators for Acoustic Energy Harvesting Academic Background With the proliferation of Internet of Things (IoT) devices, the demand for sustainable energy sources has been increasing. Traditional battery-powered systems face limitations such as finite lifespan and high maintenance costs, prompting researchers to ex...

Hierarchical Design of Pseudosymmetric Protein Nanocages

Academic Background Protein self-assembly is a ubiquitous phenomenon in biological systems, performing a wide range of functions from structural support to biochemical regulation. Despite significant progress in protein design in recent years, existing self-assembling protein structures typically rely on strict symmetry, which limits their size and...

Four-Component Protein Nanocages Designed by Programmed Symmetry Breaking

Design of Four-Component Protein Nanocages through Programmed Symmetry Breaking Academic Background Protein nanocages are highly symmetric protein assemblies widely used in vaccine development, drug delivery, and nanomaterial design. In nature, viruses often construct complex structures through symmetry breaking, particularly in high triangulation ...

Growth-Based Monolithic 3D Integration of Single-Crystal 2D Semiconductors

Research on Growth-Based Monolithic 3D Integration of Single-Crystal 2D Semiconductors Academic Background With the rapid development of the modern electronics industry, three-dimensional (3D) integration technology has gradually become an important means to enhance the performance of electronic devices. Traditional two-dimensional (2D) integrated ...

MINFLUX Fluorescence Nanoscopy in Biological Tissue

MINFLUX Fluorescence Nanoscopy in Biological Tissue

MINFLUX Nanoscopy in Biological Tissue: Breaking the Resolution Barrier of Fluorescence Microscopy Academic Background Fluorescence microscopy plays a crucial role in biological research, but its resolution is limited by the diffraction barrier, typically around 200 nanometers. In recent years, the development of super-resolution microscopy (SR) te...

Doxycycline-loaded calcium phosphate nanoparticles with a pectin coat can ameliorate lipopolysaccharide-induced neuroinflammation via enhancing AMPK

Protective Effect of Doxycycline-Loaded Calcium Phosphate Nanoparticles on LPS-Induced Neuroinflammation in Mice In the field of neuroscience research, neuroinflammation is an important pathological feature of many neurological diseases. Neuroinflammation is a complex response of the central nervous system (CNS) to various damaging triggers (such a...

Nanoligomers Targeting NF-κB and NLRP3 Reduce Neuroinflammation and Improve Cognitive Function with Aging and Tauopathy

Nanopolymer Targeting NF-κB and NLRP3 Reduces Neuroinflammation and Enhances Cognitive Function in Aging and Tauopathy Research Background Aging is a major risk factor for cognitive decline and most neurodegenerative diseases, such as Alzheimer’s disease (AD). These cognitive declines are closely related to the pathological aggregation of Tau prote...

iSCAT Microscopy and Particle Tracking with Tailored Spatial Coherence

iSCAT Microscopy and Particle Tracking with Tailored Spatial Coherence

Research on Interferometric Scattering Microscopy and Spatial Coherence Control for Multiparticle Tracking Background Introduction Interferometric Scattering (iSCAT) microscopy has demonstrated unparalleled performance in the field of label-free optical imaging, especially in the detection and imaging of isolated nanoparticles and molecules. Howeve...

A Numerical Analysis of Rectangular Open Channel Embedded TiO2-Au-MXene Employed PCF Biosensor for Brain Tumor Diagnosis

Numerical Analysis of Rectangular Open-Channel PCF Biosensor Embedded with TiO2-Au-MXene for Brain Tumor Diagnosis Academic Background and Problem Statement In recent years, the development of cost-effective and highly reliable biosensors has become a research hotspot. These sensors aim to detect minute concentrations of analytes and cover a wide a...