Oral-Anatomical Knowledge-Informed Semi-Supervised Learning for 3D Dental CBCT Segmentation and Lesion Detection

Academic Background and Research Motivation In the field of dental healthcare, Cone Beam Computed Tomography (CBCT) is a widely used three-dimensional imaging technique. CBCT provides three-dimensional images of the oral cavity and is particularly effective in diagnosing odontogenic lesions. However, the segmentation of CBCT images—labeling each vo...

Multi-Task Aquatic Toxicity Prediction Model Based on Multi-Level Features Fusion

Academic Background With the growing threat of organic compounds to environmental pollution, studying the toxic responses of different aquatic organisms to these compounds has become crucial. Such research not only helps assess the potential ecological impacts of pollutants on the overall aquatic ecosystem but also provides significant scientific f...

Resistive Memory-Based Zero-Shot Liquid State Machine for Multimodal Event Data Learning

Novel Resistive Memory-Driven Zero-Shot Multimodal Event Learning System: A Report on Hardware-Software Co-Design Academic Background The human brain is a complex spiking neural network (SNN) capable of zero-shot learning in multimodal signals with minimal power consumption, allowing generalization of existing knowledge to address new tasks. Howeve...

Efficient Scaling of Large Language Models with Mixture of Experts and 3D Analog In-Memory Computing

Efficient Scaling of Large Language Models with Mixture of Experts and 3D Analog In-Memory Computing Academic Background In recent years, large language models (LLMs) have demonstrated remarkable capabilities in natural language processing, text generation, and other fields. However, as the scale of these models continues to grow, the costs of trai...

Multimodal Learning for Mapping Genotype–Phenotype Dynamics

Multimodal Learning Reveals Genotype–Phenotype Dynamics Background The complex relationship between genotype and phenotype has long been a central question in biology. Genotype refers to the genetic information of an organism, while phenotype is the manifestation of this genetic information in a specific environment. Although Wilhelm Johannsen intr...

Leveraging Pharmacovigilance Data to Predict Population-Scale Toxicity Profiles of Checkpoint Inhibitor Immunotherapy

Predicting and Monitoring the Toxicity of Immune Checkpoint Inhibitors: Breakthrough Application of the DysPred Deep Learning Framework Academic Background Immune checkpoint inhibitors (ICIs) represent a major breakthrough in cancer immunotherapy in recent years, enhancing the body’s antitumor immune response by inhibiting immune checkpoint signali...