Relationship Between Structural and Functional Network Connectivity Changes for Patients with Traumatic Brain Injury and Chronic Health Symptoms

Medicine, Neurology, Medical Imaging,
traumatic brain injury   structural connectivity   functional connectivity   chronic symptoms   brain networks   neuroimaging   biomarkers  

Study on Structural and Functional Network Connectivity Changes in Patients with Traumatic Brain Injury Background Introduction Traumatic Brain Injury (TBI) is a common neurological disorder that can lead to long-term cognitive, emotional, and physical symptoms. Although many patients experience symptom relief within months after the injury, a sign...

Simultaneous Detection of Eight Cancer Types Using a Multiplex Droplet Digital PCR Assay

Medicine, Oncology, Life Sciences, Biochemistry, Genetics,
cancer detection   DNA methylation   droplet digital PCR   multiplexing   biomarkers   early diagnosis   tumor prediction  

Multi-Cancer Detection Using Multiplex Droplet Digital PCR Methylation Assay Background Cancer is one of the leading causes of death worldwide, with nearly 10 million deaths reported in 2020. Although many cancers can be cured when detected and treated early, many patients are still diagnosed at advanced stages, leading to poor treatment outcomes. ...

Global Profiling of Alternative Splicing in Non-Small Cell Lung Cancer Reveals Novel Histological and Population Differences

Medicine, Oncology, Life Sciences, Biochemistry, Genetics,
non-small cell lung cancer   alternative splicing   population differences   tumor biology   biomarkers   molecular subtypes   therapeutic targets  

Global Profiling of Alternative Splicing in Non-Small Cell Lung Cancer Reveals Novel Histological and Population Differences Academic Background Lung cancer is one of the most frequently diagnosed cancers in the United States, with non-small cell lung cancer (NSCLC) accounting for the majority of cases. Among NSCLC, lung adenocarcinoma (LUAD) and l...

Whole-Genome Analysis of Plasma Fibrinogen Reveals Population-Differentiated Genetic Regulators with Putative Liver Roles

Medicine, Hepatobiliary System, Hematology, Cardiovascular System, Life Sciences, Genetics,
plasma fibrinogen   whole-genome analysis   genetic regulation   population differentiation   liver roles   genetic variation   biomarkers  

Whole-Genome Analysis of Plasma Fibrinogen Reveals Population-Differentiated Genetic Regulators with Potential Liver Roles Academic Background Fibrinogen is a crucial coagulation factor and acute-phase reactive protein. Under normal physiological conditions, fibrinogen is abundant in circulation, but during the acute inflammatory response, transcri...

Validation of a Prognostic Blood-Based Sphingolipid Panel for Men with Localized Prostate Cancer Followed on Active Surveillance

Medicine, Urology, Oncology,
sphingolipids   prostate cancer   active surveillance   biomarkers   risk stratification  

Study on a Prognostic Blood-Based Sphingolipid Panel for Men with Localized Prostate Cancer on Active Surveillance Academic Background Prostate cancer is one of the most common cancers among men globally, particularly for those with low- and intermediate-risk prostate cancer, where active surveillance (AS) has become the preferred management strate...