Exploring Biomarkers and Biosensors for Motion Sickness: Innovative Approaches to Diagnostic Challenges Motion sickness (MS) is a common syndrome experienced by humans, triggered by unnatural motions such as those encountered during transportation or virtual reality (VR). It manifests through symptoms like headaches, nausea, vomiting, cold sweats, ...

New Advances in Dual-Targeting Antisense Oligonucleotide Therapy for Duchenne Muscular Dystrophy: Phase 1⁄2 Clinical Trial of Brogidirsen Background Duchenne Muscular Dystrophy (DMD) is a fatal genetic disorder primarily affecting skeletal and cardiac muscles, leading to early loss of mobility and, eventually, organ failure. Currently, there is no ...

Background Introduction This study focuses on malignant pleural mesothelioma (MPM), a rare and highly lethal cancer strongly associated with asbestos exposure. Most patients are diagnosed at advanced stages, with a survival time of only 12 to 15 months, and traditional treatments revolve around platinum-based chemotherapy. However, treatment paradi...

Phenotypic Plasticity of TREM1+ Mono-Macrophages Mediated by Radiotherapy Combined with Immunochemotherapy in Locally Advanced Rectal Cancer: A Comprehensive Multi-Omics Study Background Introduction Rectal cancer is the second leading cause of cancer-related deaths worldwide, accounting for one-third of all colorectal cancer cases. While surgical ...

Novel Early Diagnosis Method for Lung Adenocarcinoma Based on DNA Methylation in Peripheral Blood Mononuclear Cells Background Lung adenocarcinoma (LUAD) is one of the leading causes of cancer-related deaths worldwide, accounting for approximately 40% of lung cancer cases. Despite significant advancements in treatment, the prognosis of LUAD remains...