Accelerating the Discovery of Ionizable Lipids for mRNA Delivery using Machine Learning and Combinatorial Chemistry Research Background To fully realize the potential of mRNA therapies, it is essential to expand the toolkit of lipid nanoparticles (LNPs). However, a key bottleneck in LNP development is identifying new ionizable lipids. Previous stud...

With the continuous advancement of data acquisition technology, obtaining large amounts of high-dimensional data containing multiple features has become very easy, such as images and vision data. However, traditional machine learning methods, especially those based on vectors and matrices, face challenges such as the curse of dimensionality, increa...

Autonomous Navigation and Walking Wheel-Leg Robot Background Introduction The acceleration of urbanization has posed significant challenges for supply chain logistics, especially for last-mile delivery. As traffic pressure increases and the demand for faster delivery services rises, particularly with complex routes indoors and on city streets, trad...

Research Report on the Analysis of Immunological Characteristics of Peripheral Blood in Cancer Patients Cancer is a major and pervasive health problem globally. Despite significant advances in cancer treatment in recent years, many challenges remain, including how to accurately predict patients’ responses to various treatments. Immunotherapy, parti...

Background and Research Motivation Parkinson’s Disease (PD) is a neurodegenerative disorder primarily affecting patients’ motor abilities, leading to tremors, bradykinesia, limb rigidity, and problems with gait and balance. These motor deficits significantly impact patients’ ability to live independently and their quality of life. Statistics predic...