Academic Background The COVID-19 pandemic has had a significant impact on global public health systems. Although the pandemic has somewhat subsided, its complex immunopathological mechanisms, long-term sequelae (such as “long COVID”), and the potential for similar threats in the future continue to drive in-depth research. Severe COVID-19 cases are ...

Academic Background Frontotemporal Dementia (FTD) is a group of progressive neurodegenerative diseases characterized primarily by behavioral changes, language impairment, or motor dysfunction. Although the incidence of FTD is lower than that of Alzheimer’s Disease (AD), it remains one of the leading causes of early-onset dementia. The molecular bas...

Phosphatidylinositol Promotes Pituitary Adenoma Cell Proliferation and Invasion by Regulating POU1F1 Expression Background Pituitary adenoma (PA) is one of the most common primary intracranial tumors, accounting for approximately 15% of all intracranial tumors. Although most pituitary adenomas are benign, about 30% of them are invasive, known as in...

Multimodal Imaging Study of the Tumor Microenvironment in Colorectal Cancer: Revealing Spatial Heterogeneity Academic Background Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, with its complexity and heterogeneity posing significant challenges for treatment and prognosis prediction. The tumor microe...

Proteomic Subtyping of Small Cell Lung Cancer: Analysis of Prognosis and Treatment Strategies Research Background Small Cell Lung Cancer (SCLC) is a highly malignant and heterogeneous cancer characterized by rapid growth, early metastasis, and drug resistance, which limits treatment options and challenges prognostic prediction models. Current genom...