Enhancing Angiogenesis and Osseointegration through a Double Gyroid Ti6Al4V Scaffold with Triply Periodic Minimal Surface

Application of Double Gyroid Titanium Alloy Scaffolds Based on Triply Periodic Minimal Surface Structures in Bone Repair Academic Background Bone defect repair is a significant challenge in the field of orthopedics, especially in cases of critical-size bone defects caused by trauma, tumors, inflammation, and other diseases. Currently, the commonly ...

Magnesium and Gallium-Co-loaded Microspheres Accelerate Bone Repair via Osteogenesis and Antibiosis

Research on Magnesium and Gallium Co-loaded Microspheres Accelerating Bone Repair Academic Background Bone defects are a common clinical challenge, often caused by infection, tumor resection, or mechanical trauma. Bone defects not only affect patients’ quality of life but may also lead to functional loss. Although bone grafting is currently the pri...

Novel Heart Valve Leaflet Designs with Stiff Polymeric Materials and Biomimetic Kinematics

Novel Heart Valve Leaflet Design: Research Based on High-Stiffness Polymeric Materials and Biomimetic Kinematics Academic Background Heart valve disease is a significant global health issue, with over 850,000 patients requiring heart valve replacement surgery annually. Currently, the heart valves used in clinical practice are mainly divided into tw...

Cav3.3-Mediated Endochondral Ossification in a Three-Dimensional Bioprinted GelMA Hydrogel

Cav3.3-Mediated Endochondral Ossification in a Three-Dimensional Bioprinted GelMA Hydrogel

Study on Cav3.3-Mediated Endochondral Ossification in 3D Bioprinted GelMA Hydrogel Research Background Bone development is a complex process, in which the growth plate (GP) plays a crucial role in the longitudinal growth of long bones. The growth plate regulates bone maturation through the process of endochondral ossification (EO). However, GP dysf...

Photocrosslinkable Human Amniotic Membrane Hydrogel for Recovery from Spinal Cord Injury

Photocrosslinked Human Amniotic Membrane Hydrogel for Spinal Cord Injury Repair Academic Background Spinal Cord Injury (SCI) is a severe neurological disorder that often leads to loss of motor function and a decline in the quality of life for patients. Despite significant advancements in tissue engineering and regenerative medicine in recent years,...