Extreme Compression and Reconstruction of Protein Sequence Space: A Breakthrough Study on EvoAI Background Protein design and optimization have become central challenges in fields like biotechnology, medicine, and synthetic biology. The functions of proteins are determined by their sequences and structures, but this functional sequence space is hig...

ONIX: An Open-Source Platform for Multimodal Neural Recording and Perturbation During Naturalistic Behavior Research Background and Significance In recent years, significant advances have been made in large-scale neural population recording technology and studies on animal behavior in the field of neuroscience. However, these two demands often conf...

Fully Automated Microfluidic Chip-Based Embryo Sexing Technology Academic Background In the egg-laying poultry industry, newly hatched male chicks are often culled immediately after hatching, as they neither lay eggs nor produce high-quality meat. Each year, approximately 372 million male chicks are culled in the European Union. This practice has s...

Development of an Engineered Direct Electron Transfer Enzyme for Continuous Levodopa Monitoring Background Parkinson’s Disease (PD) is a chronic neurodegenerative disease that affects millions of people worldwide. It is characterized by the loss of dopaminergic neurons in the substantia nigra and the presence of α-synuclein aggregations forming Lew...

Early Detection of Uveal Melanoma Using Electrical Impedance Spectroscopy Academic Background Uveal Melanoma (UM) is the most common primary intraocular malignancy in adults, characterized by high aggressiveness, which can lead to vision loss and even life-threatening outcomes. Early detection and timely treatment are crucial for preserving vision ...