Robust Engraftment of Acute Myeloid Leukemia (AML) in Humanized Scaffolds Background Acute myeloid leukemia (AML) is a malignant blood disorder that poses significant challenges in treatment and research. Patient-derived xenograft (PDX) models are crucial tools for studying AML, but existing PDX models are often complex and labor-intensive, limitin...

Effects of Altered Haptic Feedback Gain on Balance and Its Neural Mechanisms Background In daily life, human balance control relies on multiple sensory inputs, including vision, vestibular sensation, and proprioception. Haptic feedback also plays a crucial role in balance control, especially when touching a fixed object, as it significantly reduces...

The Impact of Nanotopography on Cellular Metabolic Activities: Multimodal Imaging Reveals New Insights Academic Background In the field of biomedicine, the interaction between cells and material surfaces is crucial for studying cell behavior, tissue engineering, and regenerative medicine. Nanoscale surface topography (nanotopography) has been shown...

Research on the Modulation of Physical Properties of Biomaterials to Enhance Vascularization Background Introduction In the fields of tissue engineering and regenerative medicine, the formation of a vascular system and adequate blood perfusion are crucial for ensuring the supply of nutrients and oxygen within biomaterials. However, existing biomate...

Application of Electrospun Fibers in Modulating Foreign Body Response Background Introduction In the field of biomedicine, the use of implantable medical devices (such as subcutaneous implants) is becoming increasingly widespread. However, these devices often trigger an immune response in the host after implantation, known as the Foreign Body Respo...