Topological Organization of the Brain Network in Patients with Primary Angle-Closure Glaucoma through Graph Theory Analysis

Topological Organization of the Brain Network in Patients with Primary Angle-Closure Glaucoma through Graph Theory Analysis

Graph Theory Analysis of Brain Network Topology Structure in Patients with Primary Angle-Closure Glaucoma Research Background Glaucoma is a global blinding eye disease characterized by optic nerve damage and elevated intraocular pressure (IOP) (Kang and Tanna 2021). Among various types of glaucoma, Primary Angle-Closure Glaucoma (PACG) is particula...

Functional Connectivity Alterations in Patients with Post-Stroke Epilepsy Based on Source-Level EEG and Graph Theory

Research Report on Changes in Functional Connectivity in Post-Stroke Epilepsy (PSE) Patients Based on Source-Level EEG and Graph Theory Research Background Epilepsy has various etiologies, including idiopathic, congenital, head trauma, central nervous system infections, brain tumors, neurodegenerative diseases, and cerebrovascular diseases. Among t...

Predicting Drug-Target Affinity by Learning Protein Knowledge from Biological Networks

Predicting Drug-Target Affinity Based on Learning Protein Knowledge from Biological Networks Background The prediction of drug-target affinity (DTA) plays a crucial role in drug discovery. Efficient and accurate DTA prediction can significantly reduce the time and economic costs of new drug development. In recent years, the explosive development of...

Decreased Thalamocortical Connectivity in Resolved Rolandic Epilepsy

Decreased Thalamocortical Connectivity in Resolved Rolandic Epilepsy

Thalamocortical Connectivity Reduction in Rolandic Epilepsy Rolandic Epilepsy (RE), also known as self-limited epilepsy with centrotemporal spikes (SELECTS), is the most common localized developmental epileptic encephalopathy. This type of epilepsy is typically accompanied by transient mild to severe cognitive symptoms, sleep-related rolandic spike...

Pupillometry Reveals Resting State Alpha Power Correlates with Individual Differences in Adult Auditory Language Comprehension

Study on the Correlation between Adult Auditory Language Comprehension and Resting-State Alpha Wave Power Academic Background and Research Question Although individual differences in adult language processing have been documented in literature, the neural basis largely remains to be explored. Existing research primarily focuses on how general cogni...