Evomoe: Evolutionary Mixture-of-Experts for SSVEP-EEG Classification with User-Independent Training

Interpretation of “EVOMOE: Evolutionary Mixture-of-Experts for SSVEP-EEG Classification with User-Independent Training” 1. Research Background and Problem Statement Brain-computer interface (BCI) technology has recently shown broad application prospects in neuroengineering, assistive technology for disabilities, rehabilitation, emotion recognition,...

Generative Reconstruction of Multimodal Cardiac Waveforms from a Single Vibrational Cardiography Sensor

Multimodal Cardiovascular Waveform Generation from a Single Vibrational Cardiography Sensor Background Cardiovascular disease (CVD) is one of the leading causes of morbidity and mortality worldwide, affecting hundreds of millions of patients each year and imposing a tremendous burden on global healthcare systems. According to literature, billions o...

From Digital Twins in Healthcare to the Virtual Human Twin: A Moon-Shot Project for Digital Health Research

From Digital Twin to Virtual Human Twin: A “Moonshot” Project in Digital Health 1. Academic Background and Research Motivation Currently, the global healthcare system continues to face numerous unmet clinical and social needs, which manifest as a lack of treatment options, insufficient and expensive medical resources, lengthy waiting times, and ina...

Epigenetic Editing at Individual Age-Associated CpGs Affects the Genome-wide Epigenetic Aging Landscape

Unveiling the Mystery of the Epigenetic Aging Clock: A Review of Research on the Impact of Epigenetic Editing at Single Age-Associated CpG Sites on the Genome-wide Epigenetic Aging Landscape I. Research Background and Scientific Questions Epigenetics, especially DNA methylation, has become a cutting-edge frontier in aging mechanism research in rece...

Retrotransposon-Derived Capsid Genes PNMA1 and PNMA4 Maintain Reproductive Capacity

Mechanistic Study on How Retrotransposon-derived Capsid Genes PNMA1 and PNMA4 Maintain Reproductive Capacity — A New Research Review from Nature Aging I. Research Background and Scientific Significance Nearly half of the DNA in the human and mammalian genome is made up of retrotransposons, sequences that originally existed as “parasitic molecules” ...