Exploring the Applications of Single-Molecule Systems for Detection and Monitoring of Plasma-Circulating Nucleosomes and Oncoproteins in Diffuse Midline Glioma Research Background and Problem Overview Diffuse Midline Glioma (DMG) is a highly aggressive brain tumor primarily affecting children with extremely high mortality rates. This type of tumor ...

The Potential of Oncolytic Cytomegaloviruses Expressing EGFR-Retargeted Fusogenic Glycoprotein Complex and Drug-Controlled IL-12 in Cancer Immunotherapy Background and Objectives In recent years, cancer viroimmunotherapy has emerged as a promising research focus in the field of cancer treatment. This therapy leverages viruses to infect tumor cells,...

Using Liposomal Doxorubicin Neoadjuvant Chemotherapy to Enhance Immune Protection of Tumor Membrane Antigen-Based Nanovaccine Background and Significance Surgical resection remains the primary treatment for solid tumors, but postoperative tumor recurrence and metastasis continue to be major challenges. A promising emerging strategy in personalized ...

Research on a New Platform for Tumor-Specific Drug Delivery Targeting the Warburg Effect Cancer remains a global health challenge. Traditional cancer treatments, such as chemotherapy and radiotherapy, often come with significant side effects due to their inability to distinguish between tumor tissues and healthy tissues, leading to damage in the la...

Targeting CD70 with iPSC-Derived CAR-NK Cell Therapy Background and Objectives of the Study Over the past decade, cellular therapy for cancer has revolutionized traditional treatment concepts by introducing the idea of a “living drug.” In particular, chimeric antigen receptor T cell (CAR-T) therapy has drastically improved the efficacy of immunothe...