Microbial Reduction of Fe(III)-Bearing Solids Recovered from Hydraulic Fracturing Flowback Water: Implications for Wastewater Treatment

Hydraulic fracturing is a technique used to extract natural gas from unconventional reservoirs, but it generates large volumes of flowback and produced water. These waters contain complex mixtures of organic and inorganic constituents, particularly the solids associated with these fluids, which are often rich in iron (Fe), toxic organics, heavy met...

Bacterial Toxicity of Sulfidated Nanoscale Zerovalent Iron in Aerobic and Anaerobic Systems: Implications for Chlorinated Solvent Clean-Up Strategies

Academic Background The widespread use and improper disposal of chlorinated solvents (such as perchloroethylene and trichloroethylene) have led to severe contamination of soil and groundwater worldwide. These pollutants not only threaten groundwater security but may also affect human health through the food chain. Although traditional microbial red...

MostPlas: A Self-Correction Multi-Label Learning Model for Plasmid Host Range Prediction

Plasmids are small, circular, double-stranded DNA molecules that exist independently of chromosomal DNA in bacteria. They facilitate horizontal gene transfer, enabling host bacteria to acquire beneficial traits such as antibiotic resistance and metal resistance. Some plasmids can transfer, replicate, or persist in multiple microorganisms, and these...

Trajectory Alignment of Gene Expression Dynamics

The advent of single-cell RNA sequencing (scRNA-seq) technology has provided unprecedented resolution for studying gene expression dynamics during cell development and differentiation. However, due to the complexity of biological processes, cell developmental trajectories under different conditions are often asymmetric, posing challenges for data i...

Impact of Omega-3 Fatty Acids on Hypertriglyceridemia, Lipidomics, and Gut Microbiome in Patients with Type 2 Diabetes

Impact of Omega-3 Fatty Acids on Lipidomics and Gut Microbiome in Patients with Type 2 Diabetes Background Type 2 Diabetes (T2D) is a common metabolic disorder worldwide, often accompanied by lipid abnormalities such as hypertriglyceridemia (HTG). Lipid abnormalities are significant risk factors for cardiovascular disease (CVD), especially high tri...

Melatonin Alleviates High Temperature Exposure Induced Fetal Growth Restriction via the Gut-Placenta-Fetus Axis in Pregnant Mice

Melatonin Alleviates High Temperature Exposure-Induced Fetal Growth Restriction via the Gut-Placenta-Fetus Axis Research Background Global climate warming has become a significant threat to human health, particularly affecting pregnant women and fetuses. Studies have shown that high-temperature exposure increases the risk of adverse pregnancy outco...