Ensemble Learning Based on Matrix Completion Improves Microbe-Disease Association Prediction

Academic Background and Research Problem Microorganisms, as one of the most widely distributed forms of life on Earth, are closely related to oceans, soil, and the human body. The human body contains approximately 350 trillion microbial cells, which are intricately linked to human health and the onset and progression of diseases. In recent years, w...

Antigen Spatial-Matching Polyaptamer Nanostructure to Block Coronavirus Infection and Alleviate Inflammation

Academic Background In recent years, multiple outbreaks caused by coronaviruses have occurred globally, such as SARS (Severe Acute Respiratory Syndrome), MERS (Middle East Respiratory Syndrome), and COVID-19 (Novel Coronavirus Pneumonia). These pandemics have not only posed a serious threat to human health but also exposed the inadequacy of emergen...

Live Bacterial Chemistry in Biomedicine

Background Introduction The application of live bacteria in the biomedical field has garnered significant attention in recent years. Traditionally, bacteria were viewed as pathogens that needed to be eradicated. However, with the advancement of modern bacteriology, there has been a growing recognition of the complex symbiotic relationship between b...

Pseudomonas fluorescens–Based Biogenic Silver Nanoparticles: A Green Solution for Brown Leaf Spot Disease in Rice

Academic Background Rice (Oryza sativa L.) is a globally important food crop, providing a primary source of calories for approximately one-fifth of the world’s population. However, rice production faces various biotic and abiotic stresses, leading to reduced yields. Among these, rice brown leaf spot disease, caused by the fungal pathogen Cochliobol...

Synthesis, Physicochemical Characterization, and Antimicrobial Evaluation of Ureasil-Polyether Coatings with Silver Nanoparticles for Hospital Devices

Research Background Nosocomial infections are a common and serious problem in healthcare settings, particularly on reusable medical devices, where cross-contamination and biofilm formation are major causes. To address this challenge, researchers have begun exploring the use of coating materials containing metallic nanoparticles to prevent microbial...

Structural, Optical, and Antibacterial Properties of NiO and BaO Doped NiO Prepared by Co-Precipitation Method

Academic Background Nickel oxide (NiO), as a p-type semiconductor, has garnered significant attention due to its exceptional optical properties, chemical stability, and extensive applications in optoelectronics, photocatalysis, and biosensors. NiO’s high transparency, adjustable electrical conductivity, and wide bandgap make it an ideal material fo...