Melatonin Alleviates High Temperature Exposure Induced Fetal Growth Restriction via the Gut-Placenta-Fetus Axis in Pregnant Mice

Medicine, Obstetrics and Gynecology, Endocrinology, Life Sciences, Microbiology,
heat stress   LPS   gut microbial dysbiosis   placental barrier   melatonin  

Melatonin Alleviates High Temperature Exposure-Induced Fetal Growth Restriction via the Gut-Placenta-Fetus Axis Research Background Global climate warming has become a significant threat to human health, particularly affecting pregnant women and fetuses. Studies have shown that high-temperature exposure increases the risk of adverse pregnancy outco...

Achieving Healthy Aging Through Gut Microbiota-Directed Dietary Intervention: Focusing on Microbial Biomarkers and Host Mechanisms

Medicine, Geriatrics, Gastroenterology, Life Sciences, Microbiology,
aging   gut microbiota   longevity   microbial biomarkers   host mechanisms   diet intervention  

Achieving Healthy Aging through Gut Microbiota-Directed Dietary Intervention: Focusing on Microbial Biomarkers and Host Mechanisms Academic Background With the intensification of global population aging, preventing age-related diseases and extending healthy life expectancy have become critical issues in global public health. Gut microbiota has been...

Identification of a Transcription Factor Aomsn2 of the HOG1 Signaling Pathway Contributes to Fungal Growth, Development and Pathogenicity in Arthrobotrys oligospora

Medicine, Life Sciences, Cell Biology, Biochemistry, Microbiology,
fungus   transcription factor   HOG1 signaling pathway   growth   pathogenicity  

The Role of Transcription Factor AoMsn2 in the Hog1 Signaling Pathway in Fungal Growth, Development, and Pathogenicity Background Plant-parasitic nematodes cause significant annual losses to agriculture, while nematode-trapping fungi (NT fungi), due to their ability to capture nematodes by forming specialized trapping structures, have gradually bec...

Inflammatory Proteins and Hidradenitis Suppurativa: Insights from Genetic Correlation and Mendelian Randomization

Medicine, Life Sciences, Immunology, Genetics, Microbiology,
Hidradenitis Suppurativa   Inflammatory Proteins   Genetic Correlation   Mendelian Randomization   Causal Relationship  

Inflammatory Proteins and Hidradenitis Suppurativa: Insights from Genetic Correlation and Mendelian Randomization Studies Research Background Hidradenitis Suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent nodules, abscesses, and sinus tracts, commonly found in areas of skin friction such as the armpits, groin, peria...

New Advances in Periodontal Functional Materials Based on Antibacterial, Anti-inflammatory, and Tissue Regeneration Strategies

Chemistry, Nanoscience, Polymer Chemistry, Medicinal Chemistry, Medicine, Oral Sciences, Life Sciences, Biochemistry, Bioengineering, Immunology, Microbiology,
periodontitis   antibacterial materials   anti-inflammatory therapy   tissue regeneration   multifunctional materials   biomaterials   innovative treatment  

A Review on Novel Periodontal Functional Materials: Comprehensive Exploration of Antibacterial, Anti-inflammatory, and Tissue Regeneration Strategies Academic Background and Research Significance With the accelerating trend of global population aging, the concern for oral health issues is increasing. Periodontitis, as a common bacterial infectious ...

Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-positive breast cancer risk

Medicine, Endocrinology, Oncology, Life Sciences, Cell Biology, Biochemistry, Microbiology,
breast microbiome   endocrine-targeting therapies   breast cancer risk   probiotics   tissue metabolism   tumorigenesis   estrogen receptor  

Exploring the Impact of Endocrine-Targeting Therapies on Breast Microbiota and Their Potential in Breast Cancer Prevention and Treatment Breast cancer is one of the most commonly diagnosed types of cancer in women. Despite significant advancements in diagnosis and treatment, the mortality rate remains high, with over 40,000 deaths annually in the U...