A Distinct Hypothalamus–Habenula Circuit Governs Risk Preference

Study on the Hypothalamus-Habenula Circuit Regulating Risk Preference Academic Background In complex and uncertain environments, animals need to assess risks to make survival-favorable decisions. When faced with safe and risky options, animals usually exhibit a strong preference for one option, which remains consistent over time. However, how this ...

A Large Field-of-View, Single-Cell-Resolution Two- and Three-Photon Microscope for Deep and Wide Imaging

A Large Field-of-View, Single-Cell-Resolution Two- and Three-Photon Microscope for Deep and Wide Imaging

Large field-of-view, single-cell-resolution two- and three-photon microscope for deep and wide imaging Research Background and Problem Statement Multiphoton microscopy (MPM) is a powerful tool for deep tissue imaging, especially in the study of brain function in vivo. However, while traditional two-photon microscopy (2PM) can achieve a larger imagi...

UVC LED System for Prolonging the Postharvest Shelf Life of Murcotts

Academic Background Citrus fruits have long been favored by consumers for their rich nutritional value and unique flavor. However, citrus fruits are highly susceptible to diseases during postharvest storage, particularly green mold caused by Penicillium digitatum. This disease leads to fruit decay and significantly shortens storage life. Traditiona...

Early Detection of Pancreatic Cancer by a High-Throughput Protease-Activated Nanosensor Assay

New Method for Early Detection of Pancreatic Cancer—A Protease-Activated Nanosensor Assay Background Pancreatic Ductal Adenocarcinoma (PDAC) is one of the leading causes of cancer-related deaths worldwide. Due to its nonspecific early symptoms, most patients are diagnosed at advanced stages, resulting in limited treatment options and poor prognosis...

In Vivo Expansion of Gene-Targeted Hepatocytes through Transient Inhibition of an Essential Gene

Breakthrough in Gene Therapy: Repair Drive Technology Enables In Vivo Expansion of Hepatocytes Academic Background Gene therapy has become a hot topic in medical research in recent years, especially for liver diseases. Due to the central role of the liver in metabolism, it has become a critical target for research. Although existing gene-editing te...