Recommendations for Implementing the HEvolution Alliance for Aging Biomarkers Initiative

Promoting Healthy Longevity: Implementation Recommendations for the Hevolution Alliance for Aging Biomarkers Initiative Academic Background and Research Motivation With the intensification of global population aging, human life expectancy has significantly increased, but the growth in healthy life expectancy (i.e., years lived in good health) has b...

FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy

Research Background and Problem Introduction Protein O-GlcNAc glycosylation is an important post-translational modification that plays a critical role in cellular metabolic plasticity. Aberrant O-GlcNAc glycosylation levels have been observed in various cancers, including endometrial cancer (EC), a common malignancy in women. However, clinical char...

Control of Movement: Kinematic Hand Synergies Differ Between Reach-and-Grasp and Functional Object Manipulation

Human Hand Movement Control—Differences in Kinematics Between Functional Object Manipulation and Grasping Actions Academic Background The functionality of the human hand plays a crucial role in daily life, particularly through its dexterity, which allows us to use tools to complete various complex tasks. However, millions of people lose hand functi...

Modular Brain-Machine Interface for Neurorecording, Neurostimulation, and Drug Delivery

Modular Brain-Machine Interface for Neurorecording, Neurostimulation, and Drug Delivery

Modular Brain-Machine Interface: Innovative Breakthrough in Neurorecording, Neurostimulation, and Drug Delivery Academic Background Brain-Machine Interfaces (BMIs) are crucial tools in neuroscience and clinical medicine, enabling interactions between the brain and the external world through charge, matter, and information exchange. They are widely ...

Ultralow-Power Carbon Dioxide Sensor for Real-Time Breath Monitoring

Research on an Ultra-Low Power Carbon Dioxide Sensor for Real-Time Breath Monitoring Academic Background Carbon dioxide (CO₂) is a critical gas produced during human respiration, and its real-time monitoring is essential for diagnosing and treating respiratory diseases (e.g., asthma, dyspnea, sleep apnea) as well as metabolic disorders. Traditional...